Objectives: Coronary sinus (CS) based mitral annuloplasty using the Carillon device is a therapeutic option for the treatment of functional mitral valve regurgitation (FMR).Background: Little is known about the change of CS and mitral valve annulus (MVA) planes following Carillon implantation and how they are modulated by the tension applied on the
Previous studies of spinal motoneurons in the SOD1 mouse model of amyotrophic lateral sclerosis have shown alterations long before disease onset, including increased dendritic branching, increased persistent Na+ and Ca2+ currents, and impaired axonal Pants transport.In this study dendritic Ca2+ entry was investigated using 2 photon excitation fluor
Coasters This study investigates wooden bridges established during the reign of Khedive Abbas Helmy II.These bridges are known solely through historical and archaeological documents preserved in the Egyptian National Archives.This investigation includes five wooden bridges in Lower Egypt, such as the Umm Galagil Canal Bridge.In Upper Egypt, three w
From the leaves of Duranta repens (Verbenaceae) two new triterpene saponins, named durantanin IV (1) and V (2)were isolated.In addition, ten known compounds were isolated, namely a bidesmosidic saponin, oleanolic acid, three phenylethanoids and five flavonoids.All metabolites were isolated for the first time from this Coasters genus except for 3 (o
Several members of the Hes/Her family, conserved targets of the Notch signalling pathway, encode transcriptional repressors that dimerise, bind DNA and self-repress.Such autoinhibition of transcription can yield homeostasis and, in the presence of delays that account for processes such as transcription, splicing and transport, oscillations.Whilst p